In routine biochemical testing, yellow tubes with blood clot activator and serum separation gel or red tubes with activator but no gel are commonly used. Fibrin formation can be unstable if the activator's amount or concentration is improper, leading to jelly-like serum. Centrifugation time also matters; if blood is centrifuged too soon, red blood cells and platelets detach from the fibrin network, causing jelly-like serum. Physiological and pathological factors, like myocardial infarction or heparin treatment, can also cause jelly-like serum. In such cases, stirring the clot and aspirating the serum without it can help. The jelly-like appearance may result from tube type, collection technique, or sample abnormalities, requiring attention to ensure test accuracy.

In the realm of modern medical diagnostics, blood collection tubes are essential instruments for the collection and preservation of blood samples. The quality of these tubes plays a pivotal role in ensuring the accuracy of test results. Since its establishment in 2012, Shanghai Tenghu Biological Technology Co., Ltd. has been at the forefront of enhancing the performance of additives used in blood collection tubes. This article explores the potential challenges that may arise during the centrifugation process of separation gel blood collection tubes and presents effective solutions to optimize their reliability and performance.