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Enhancing Diagnostic Precision: Analyzing and Addressing the Centrifugation Effects of Separation Gel Blood Collection Tubes

In the realm of modern medical diagnostics, blood collection tubes are essential instruments for the collection and preservation of blood samples. The quality of these tubes plays a pivotal role in ensuring the accuracy of test results. Since its establishment in 2012, Shanghai Tenghu Biological Technology Co., Ltd. has been at the forefront of enhancing the performance of additives used in blood collection tubes. This article explores the potential challenges that may arise during the centrifugation process of separation gel blood collection tubes and presents effective solutions to optimize their reliability and performance.

The Crucial Role of Blood Collection Procedures

The blood collection process is a critical step in ensuring the optimal performance of separation gel blood collection tubes and the accuracy of diagnostic results. A meticulous technique during this stage is essential for the success of subsequent tests. Below are some common blood collection errors and their potential consequences:

Collection Errors:


After blood collection, it is vital to gently invert the tube 5-8 times to ensure thorough mixing of the blood with the additives. Neglecting to do so, or delaying the mixing process, can hinder proper interaction between the blood and coagulants. This inadequate mixing may lead to the formation of fibrin clots, which can compromise sample quality and ultimately impact the reliability of test results.


By maintaining a careful and consistent approach during blood collection, we can ensure the highest standards of diagnostic accuracy.

采血现场图

Impact of Post-Collection Placement Time

The placement time after blood collection has a significant impact on the quality of the blood sample:

Failure to Centrifuge Promptly: 


For blood collection tubes without anticoagulants, the blood will naturally coagulate. If left for too long, the serum may separate and could potentially be reabsorbed by the blood cells, affecting the serum yield. 


For tubes containing anticoagulants, prolonged placement time may lead to changes in blood cell morphology or the degradation of certain components.

Impact of Post-Collection Placement Time

Pre-Centrifugation Handling of Blood Collection Tubes

The handling of blood collection tubes before centrifugation is equally crucial. Below are some common handling mistakes that should be avoided:

1. Improper Balancing of the Centrifuge: When blood collection tubes are placed asymmetrically inside the centrifuge, it can cause vibrations during the centrifugation process. This not only disrupts the uniformity of the blood separation but can also damage the tubes.


2. Exposure to Excessive Shaking or Impact: Vigorous shaking or collisions may cause blood components that have already started to coagulate to mix, or even damage blood cells, compromising the quality of the separation and potentially affecting the test results.

Pre-Centrifugation Handling of Blood Collection Tu

Centrifugation Speed and Time Settings

The correct adjustment of centrifugation speed and time is essential for achieving optimal blood component separation.

Improper Centrifugation Settings: If the centrifugation speed is too low or the time is too short, the blood components may not separate properly. On the other hand, excessive speed or prolonged centrifugation can cause blood cells to rupture, leading to compromised sample integrity and potentially affecting the accuracy of test results.

Centrifugation Speed and Time Settings

Standardized and Precise Blood Collection Procedures are the cornerstone of ensuring the optimal performance of separation gel blood collection tubes and maintaining high testing standards. Healthcare professionals must pay close attention to every detail in the blood collection process to guarantee the reliability and effectiveness of medical diagnostics. By continually refining operational protocols and equipment configurations, we can minimize errors and enhance the overall quality of testing.


Shanghai Tenghu Biological Technology Co., Ltd. remains committed to advancing the research and development of blood collection tube additives, working hand-in-hand with healthcare professionals to drive the progress of medical testing technologies.

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Our main products including blood collection tube machine, serum separation gel, blood clot activator, anti-coagulant reagents, and medical consumables which are widely used in IVD diagnosis and other field.

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Tel: +86 13918801906

E-mail: marketing@sh-th.com.cn

Address: No.17, Lane 5, Cao Nong Road, Songjiang District, Shanghai, China

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