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Application of EDTA in the Medical Field

Application of EDTA in the Medical Field

EDTA is a widely used anticoagulant in clinical routine blood tests. It has minimal impact on blood cell agglutination and cell morphology, and can inhibit platelet aggregation.

EDTA anticoagulant blood collection tubes are widely applied in clinical hematology examinations and are compatible with various hematology analyzers. They do not cause cell shrinkage or swelling, ensuring that blood cell characteristics such as morphology and size remain close to the physiological state during testing. This guarantees the accuracy of white blood cell, red blood cell, and platelet counts and differential results.

In addition, EDTA offers excellent stability. Blood samples anticoagulated with EDTA can maintain stable composition and properties for a certain period, which means a flexible testing time and location.

 Application of EDTA in the Medical Field 1

1.Anticoagulant Principle

It mainly works by binding with calcium ions in the blood to form stable chelates, thereby preventing blood coagulation. EDTA has minimal impact on the morphology of red blood cells and white blood cells, making it suitable for routine hematological tests, especially complete blood count (CBC).

 

2.Features
2.1 Sufficient Anticoagulation: Rapidly and effectively prevents blood coagulation, ensuring the accuracy and reliability of test results.
2.2 Low Impact on Blood Cell Morphology: Effectively preserves the morphology and integrity of blood cells, making cell counting, differentiation and other results in routine blood tests closer to the real condition.
2.3 High Stability: Under conventional storage conditions, blood samples anticoagulated with EDTA can remain stable for a certain period, facilitating laboratory testing arrangements.

 Application of EDTA in the Medical Field 2

3.Precaution
3.1 Accurate Blood Volume Required: Blood collection must be performed strictly in accordance with the anticoagulant spraying volume specified for the blood collection tube (1.5mg–2.2mg per ml of blood). Either insufficient or excessive blood volume will affect the anticoagulant effect and test results.
3.2 Gentle Shaking: To avoid hemolysis of blood cells, shake the blood collection tube gently and promptly after blood collection.

 As an internationally recognized ideal anticoagulant, EDTA has virtually no effect on blood cell counts. Routine blood test, as one of the most important and widely used clinical examinations, ensures accurate and reliable test results.

 

Tenghu Biol specializes in the production of blood collection tube reagents. We supply high-quality blood collection tube reagents including EDTA K2, EDTA K3, and EDTA Na2, together with supporting auxiliary reagents such as inner wall anti-adhesive agent, anti-micro-coagulant, stabilizer, and moisturizer. These products can effectively reduce blood adhesion on the tube wall, fibrin formation, and bacterial growth. They also enhance anticoagulant effect, maintain stable platelet activity, extend sample storage time, and prevent reagents clogging in spray nozzles.

Tenghu Biol offer professional instructions and guidance. Based on customers’ testing requirements, we provide rational advice on the selection of anticoagulant types as well as their dissolution and spraying dosages, so as to ensure the scientific reliability of medical diagnosis.

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Our main products including blood collection tube machine, serum separation gel, blood clot activator, anti-coagulant reagents, and medical consumables which are widely used in IVD diagnosis and other field.

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Tel: +86 13918801906

E-mail: marketing@sh-th.com.cn

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